Last updated: September 2025
For decades ED (erectile dysfunction) treatments were limited to in-person visits and pharmacy runs. Today, telehealth and specialized services make effective, FDA‑approved options (like sildenafil and tadalafil) available by online consult, often at a fraction of traditional prices. This short guide compares top providers so you can quickly see which service fits your needs.
#1
People's Choice
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Sildenafil, tadalafil, combo formulas
From ~$2–$4 per dose (annual plans)
Format: Oral tablets & combo products
Rx required: Yes (telehealth consult)
Best for: Men who want clinic‑grade meds + subscription options
#2
People's Choice
Sildenafil, tadalafil, combo formulas
From ~$2–$4 per dose (annual plans)
Format: Oral tablets & combo products
Rx required: Yes (telehealth consult)
Best for: Men who want clinic‑grade meds + subscription options
#3
People's Choice
Sildenafil, tadalafil, chewables, mints
Price (starting): From ~$2 per dose
Format: Oral tablets, chewables, mints
Rx required: Yes
Best for: Budget-friendly, direct-to-consumer care
#4
People's Choice
Chewable sildenafil, tadalafil, vardenafil
Price (starting): Plans from ~$25/month
Format: Chewable tablets
Rx required: Yes
Best for: Men who prefer chewables over pills
#5
People's Choice
Generic sildenafil, tadalafil, vardenafil
Price (starting): From ~$2/pill (one‑time consult)
Format: Oral tablets, pharmacy delivery
Rx required: Yes
Best for: Fast, low‑cost single orders & refills
#6
People's Choice
Telemedicine visits + ED prescriptions
Price (starting): Varies (televisit + med cost)
Format: Oral tablets, pharmacy fulfillment
Rx required: Yes
Best for: People who want a full telemedicine clinic experience
#7
People's Choice
Marketplace for EMR/telehealth clinicians
Price (starting): Varies (provider-dependent)
Format: Telehealth consults + Rx to pharmacy
Rx required: Yes
Best for: Price‑conscious users who want to pick a provider
#8
People's Choice
Telehealth consult + discounted meds
Price (starting): Plans from ~$18/month (varies)
Format: Rx delivery or local pharmacy
Rx required: Yes
Best for: Users who want low-cost meds with coupon savings
Erectile Dysfunction (ED) is when a man has trouble getting or keeping an erection firm enough for sexual activity. Experiencing this occasionally is common, especially after age 40–50, but when it happens often or starts to interfere with your intimacy or confidence, it's worth talking to a healthcare provider. ED can also be a sign of underlying health issues (like heart disease, diabetes, or hormonal imbalance). Getting the right treatment can greatly improve quality of life. ED occurs when a man has difficulty achieving or maintaining an erection firm enough for satisfactory sexual performance. While occasional trouble is normal, persistent ED may point to underlying health concerns such as cardiovascular disease, diabetes, low testosterone, or psychological stressors.
Erectile dysfunction (ED) medications are prescription treatments designed to help men achieve and maintain an erection firm enough for sexual activity. They work primarily by improving blood flow to the penis during sexual stimulation.
Most ED medications belong to a class called phosphodiesterase type-5 (PDE5) inhibitors. These drugs relax blood vessels and increase circulation, making it easier to respond naturally to arousal. ED medications are generally safe when prescribed by a licensed clinician, but they are not suitable for everyone. Men with certain heart conditions or those taking nitrates should avoid PDE5 inhibitors. That’s why it’s essential to consult with a qualified provider before starting treatment.
Sildenafil is a phosphodiesterase-5 (PDE‑5) inhibitor used to treat erectile dysfunction. It works by increasing blood flow to the penis during sexual stimulation, making it easier to achieve and sustain an erection.
Tadalafil is a long-acting PDE‑5 inhibitor, often lasting up to 36 hours. This makes it a flexible option for men who want to maintain sexual spontaneity without needing to time their dose closely.
Avanafil is a newer PDE‑5 inhibitor designed to act quickly, often within 15 minutes. It is effective for many men, though it doesn’t cure ED or increase libido, and it does not prevent STIs or pregnancy.
Vardenafil improves erectile function by increasing blood flow to the penis during sexual arousal. It is another PDE‑5 inhibitor, offering similar benefits to sildenafil with some users preferring its slightly different profile.
ED treatments are most effective when prescribed under the guidance of a licensed clinician. Most men benefit from PDE‑5 inhibitors, but lifestyle changes, hormone testing, and psychological support may also be recommended. A medical evaluation is essential to find the safest and most effective path forward.
The most common symptoms of erectile dysfunction include:
- Difficulty achieving an erection
- Trouble maintaining an erection during sex
- Reduced sexual desire
- Anxiety or stress around sexual performance
Some lifestyle choices and health conditions can increase the likelihood of experiencing ED.
These include:
Chronic medical conditions: Conditions like diabetes, high cholesterol, and cardiovascular disease are strongly linked to ED.
Alcohol and drug use: Heavy or long-term use of alcohol and drugs can interfere with blood circulation and nerve function.
Smoking: Tobacco restricts blood flow and damages blood vessels, making erections more difficult to sustain.
Excess weight: Being overweight or obese raises the risk of hormone disruption and cardiovascular issues that contribute to ED.
Medication side effects: Some antidepressants, blood pressure medications, diuretics, and heart rhythm drugs may contribute to erectile difficulties.
Although erectile dysfunction (ED) is often associated with aging, it can affect men at any stage of life. A variety of health conditions and physical factors can interfere with sexual function. Some of the most common causes include:
Circulatory issues: Problems such as heart disease, high blood pressure, and poor blood flow can make it difficult to achieve or maintain an erection.
Substance misuse: Excessive alcohol use or recreational drug use can interfere with sexual performance.
Diabetes: High blood sugar damages nerves and blood vessels, both of which play a critical role in erections.
Obesity: Being significantly overweight can contribute to hormonal imbalances and vascular problems.
Neurological conditions: Diseases such as multiple sclerosis (MS) and spinal cord injuries can disrupt nerve signals.
Psychological factors: Depression, anxiety, or chronic stress can affect sexual performance.
Peyronie’s disease: The buildup of scar tissue inside the penis can cause painful or difficult erections.
Medications: Certain prescription drugs may list erectile dysfunction as a side effect.
We focused on trusted providers that:
(1) offer FDA-approved ED medications,
(2) require telehealth consultations with licensed clinicians,
(3) provide transparent pricing, and
(4) have wide U.S. availability.
#1
People's Choice
Sildenafil, tadalafil, combo formulas
From ~$2–$4 per dose (annual plans)
Format: Oral tablets & combo products
Rx required: Yes (telehealth consult)
Best for: Men who want clinic‑grade meds + subscription options
Disclaimer
This content is provided for informational purposes only and should not be taken as medical advice. Always consult a licensed healthcare provider before starting, changing, or stopping any treatment for erectile dysfunction. We may earn compensation from some of the brands featured, which can influence placement. Please confirm details with each provider before making decisions.
Advertiser Disclosure
Our site is supported through partnerships with select providers. Some of the links and offers featured here may result in compensation to us. This compensation can affect the placement and ranking of products on the page. However, our reviews and opinions are based on research and are not influenced by advertisers. While we strive to keep information accurate and current, details such as pricing, availability, and promotions may change without notice. Please review each provider’s terms and conditions before making a decision.
